Gene name:
Nr4a2 (Hzf-3;Nurr1;Rnr1) ;
Protein name:
Nuclear receptor subfamily 4 group A member 2 ;
Alternative:
Nuclear orphan receptor HZF-3 ;NUR-related factor 1 ;Regenerating liver nuclear receptor 1 (RNR-1) ;Orphan nuclear receptor NURR1 ;SL-322 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3.
Function:
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). May confer liver-specific regulation of delayed-early genes induced later in the G1 phase of regeneration along with HMR.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MPCVQAQYGS | SPQGASPASQ | SYSYHSSGEY | SSDFLTPEFV | KFSMDLTNTE |
100:
ITATTSLPSF | STFMDNYSTG | YDVKPPCLYQ | MPLSGQQSSI | KVEDIQMHNY |
150:
QQHSHLPPQS | EEMMPHSGSV | YYKPSSPPTP | STPGFQVQHS | PMWDDPGSLH |
200:
NFHQNYVATT | HMIEQRKTPV | SRLSLFSFKQ | SRPGTPVSSC | QMRFDGPLHV |
250:
PMNPEPAGSH | HVVDGQTFAV | PNPIRKPASM | GFPGLQIGHA | SQLLDTQVPS |
300:
PPSRGSPSNE | GLCAVCGDNA | ACQHYGVRTC | EGCKGFFKRT | VQKNAKYVCL |
350:
ANKNCPVDKR | RRNRCQYCRF | QKCLAVGMVK | EVVRTDSLKG | RRGRLPSKPK |
400:
SPQDPSPPSP | PVSLISALVR | AHVDSNPAMT | SLDYSRFQAN | PDYQMSGDDT |
450:
QHIQQFYDLL | TGSMEIIRGW | AEKIPGFADL | PKADQDLLFE | SAFLELFVLR |
500:
LAYRSNPVEG | KLIFCNGVVL | HRLQCVRGFG | EWIDSIVEFS | SNLQNMNIDI |
550:
SAFSCIAALA | MVTERHGLKE | PKRVEELQNK | IVNCLKDHVT | FNNGGLNRPN |
598:
YLSKLLGKLP | ELRTLCTQGL | QRIFYLKLED | LVPPPAIIDK | LFLDTLPF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
Protein for Rat Nuclear receptor subfamily 4 group A member 2
Protein for Rat Nuclear receptor subfamily 4 group A member 2
Protein for Rat Nuclear receptor subfamily 4 group A member 2
Protein for Rat Nuclear receptor subfamily 4 group A member 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Hippocampus .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
3.
"Rat nurr1 is prominently expressed in perirhinal cortex, and differentially induced in the hippocampal dentate gyrus by electroconvulsive vs. kindled seizures."
Xing G.Q.
,
Zhang L.X.
,
Zhang L.
,
Heynen T.
,
Li X.L.
,
Smith M.A.
,
Weiss S.R.B.
,
Feldman A.N.
,
Detera-Wadleigh S.
,
Chuang D.M.
,
Post R.M.
Brain Res. Mol. Brain Res.47:251-261(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY