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Index > Protein center > Nr4a2(Gene name) > Rat
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  • Nr4a2 (Gene name),
  • Nuclear receptor subfamily 4 group A member 2 (Protein name ),  NR4A2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Nr4a2(Hzf-3;Nurr1;Rnr1);
    Protein name:
    Nuclear receptor subfamily 4 group A member 2;
    Alternative:
    Nuclear orphan receptor HZF-3;NUR-related factor 1;Regenerating liver nuclear receptor 1(RNR-1);Orphan nuclear receptor NURR1;SL-322;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3.
    Function:
    Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). May confer liver-specific regulation of delayed-early genes induced later in the G1 phase of regeneration along with HMR.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    598
    Sequence:
    50:
    MPCVQAQYGS | SPQGASPASQ | SYSYHSSGEY | SSDFLTPEFV | KFSMDLTNTE | 
    100:
    ITATTSLPSF | STFMDNYSTG | YDVKPPCLYQ | MPLSGQQSSI | KVEDIQMHNY | 
    150:
    QQHSHLPPQS | EEMMPHSGSV | YYKPSSPPTP | STPGFQVQHS | PMWDDPGSLH | 
    200:
    NFHQNYVATT | HMIEQRKTPV | SRLSLFSFKQ | SRPGTPVSSC | QMRFDGPLHV | 
    250:
    PMNPEPAGSH | HVVDGQTFAV | PNPIRKPASM | GFPGLQIGHA | SQLLDTQVPS | 
    300:
    PPSRGSPSNE | GLCAVCGDNA | ACQHYGVRTC | EGCKGFFKRT | VQKNAKYVCL | 
    350:
    ANKNCPVDKR | RRNRCQYCRF | QKCLAVGMVK | EVVRTDSLKG | RRGRLPSKPK | 
    400:
    SPQDPSPPSP | PVSLISALVR | AHVDSNPAMT | SLDYSRFQAN | PDYQMSGDDT | 
    450:
    QHIQQFYDLL | TGSMEIIRGW | AEKIPGFADL | PKADQDLLFE | SAFLELFVLR | 
    500:
    LAYRSNPVEG | KLIFCNGVVL | HRLQCVRGFG | EWIDSIVEFS | SNLQNMNIDI | 
    550:
    SAFSCIAALA | MVTERHGLKE | PKRVEELQNK | IVNCLKDHVT | FNNGGLNRPN | 
    598:
    YLSKLLGKLP | ELRTLCTQGL | QRIFYLKLED | LVPPPAIIDK | LFLDTLPF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    E15148h
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    E15148m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    E15148r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    E15148b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    U15148r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    U15148b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    U15148m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    U15148h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    P15148Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    P15148Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Cat.:
    P15148Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Monoclonal Antibody for Rat Nuclear receptor subfamily 4 group A member 2
    Protein for Rat Nuclear receptor subfamily 4 group A member 2
    Protein for Rat Nuclear receptor subfamily 4 group A member 2
    Protein for Rat Nuclear receptor subfamily 4 group A member 2
    Protein for Rat Nuclear receptor subfamily 4 group A member 2

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    References
    1. 1.
      "Expression of nuclear hormone receptors within the rat hippocampus: identification of novel orphan receptors."
      Pena de Ortiz S. , Cannon M.M. , Jamieson G.A. Jr.
      Brain Res. Mol. Brain Res.23:278-283(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Hippocampus.
    2. 2.
      "RNR-1, a nuclear receptor in the NGFI-B/Nur77 family that is rapidly induced in regenerating liver."
      Scearce L.M. , Laz T.M. , Hazel T.G. , Lau L.F. , Taub R.
      J. Biol. Chem.268:8855-8861(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    3. 3.
      "Rat nurr1 is prominently expressed in perirhinal cortex, and differentially induced in the hippocampal dentate gyrus by electroconvulsive vs. kindled seizures."
      Xing G.Q. , Zhang L.X. , Zhang L. , Heynen T. , Li X.L. , Smith M.A. , Weiss S.R.B. , Feldman A.N. , Detera-Wadleigh S. , Chuang D.M. , Post R.M.
      Brain Res. Mol. Brain Res.47:251-261(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Brain.
    4. 4.
      "Immunocytochemical expression of dopamine-related transcription factors Pitx3 and Nurr1 in prenatally stressed adult rats."
      Katunar M.R. , Saez T. , Brusco A. , Antonelli M.C.
      J. Neurosci. Res.87:1014-1022(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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